
Thermo Fisher Scientific HOXD8 Monoclonal Antibody (OTI2B6), TrueMAB
HOXD8 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot에 최적화되어 있으며, Human과 Mouse 시료에 반응. 동결건조 형태로 제공되며, 보존제 무첨가 PBS 버퍼에 용해 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 69–290 of human HOXD8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The HOXD8 gene belongs to the homeobox family of transcription factors, which play a critical role in morphogenesis in multicellular organisms. Mammals have four homeobox gene clusters (HOXA, HOXB, HOXC, HOXD) located on different chromosomes.
HOXD8 is part of the HOXD cluster on chromosome 2. Deletions involving this cluster are associated with severe limb and genital abnormalities. Beyond embryogenesis, HOXD8 may also function in adult urogenital tract regulation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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