Thermo Fisher Scientific EphA4 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Pig (100%);
  Opossum, Platypus, Lizard (95%);
  Turkey, Chicken (90%).
• For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
• After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family.
EPH and EPH-related receptors are involved in developmental processes, particularly in the nervous system.
Receptors in this subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats.
Ephrin receptors are divided into two groups based on extracellular domain sequence similarity and ligand-binding affinities (ephrin-A and ephrin-B).
EphA4 encodes a protein that binds ephrin-A ligands.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.