Thermo Fisher Scientific EphA4 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) [IHC (P)]

• Tested Dilution: 6 µg/mL

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:200

Product Specifications

Product Specific Information

Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Marmoset (100%); Dog, Panda, Horse (94%); Bovine, Bat, Hamster, Elephant, Pig, Opossum, Turkey, Chicken (88%); Mouse, Rat, Rabbit, Platypus, Lizard, Xenopus (81%).

For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Target Information

EPHA4 belongs to the ephrin receptor subfamily of the protein tyrosine kinase family.
EPH and EPH-related receptors have been implicated in developmental events, particularly in the nervous system.
Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and two fibronectin type III repeats.
The ephrin receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
EphA4 encodes a protein that binds ephrin-A ligands.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.