Thermo Fisher Scientific TCF19 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

TCF19 (AAH44632.1, 1 a.a. approximately 345 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TCF19,uniProtId:Q9Y242-1,ncbiNodeId:9606,antigenRange:1-345,antigenLength:345,antigenImageFileName:H00006941-D01P_TCF19_Q9Y242-1_Rabbit.svg,antigenImageFileNamePDP:H00006941-D01P_TCF19_Q9Y242-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MLPCFQLLRI GGGRGGDLYT FHPPAGAGCT YRLGHRADLC DVALRPQQEP GLISGIHAEL HAEPRGDDWR VSLEDHSSQG TLVNNVRLPR GHRLELSDGD LLTFGPEGPP GTSPSEFYFM FQQVRVKPQD FAAITIPRSR GEARVGAGFR PMLPSQGAPQ RPLSTFSPAP KATLILNSIG SLSKLRPQPL TFSPSWGGPK SLPVPAPPGE VGTTPSAPPQ RNRRKSVHRV LAELDDESEP PENPPPVLME PRKKLRVDKA PLTPTGNRRG RPRKYPVSAP MAPPAVGGGE PCAAPCCCLP QEETVAWVQC DGCDVWFHVA CVGCSIQAAR EADFRCPGCR AGIQT

Target Information

TCF-19 (transcription factor 19), also known as SC1 or SC1-1, is a 345 amino acid protein that contains one FHA domain, a proline-rich domain and one PHD-type zinc finger. Localizing to the nucleus, TCF-19 is a growth regulated protein that is believed to function as a trans-activating factor with a role in the transcription of genes involved in the late stages of cell cycle progression (G1 to S transition or entry of cells into G2 and mitosis). TCF-19 is expressed preferentially in the G1-S phase of the cell cycle. The gene encoding TCF-19 localizes to a critical region on chromosome 6 that has been associated with psoriasis vulgaris, a disorder of the skin that is characterized by hyperproliferation of epidermal cells. This suggests that TCF-19, via its regulation of late cell cycle-specific genes, may play a role in the development of this disorder.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.