Thermo Fisher Scientific DACH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DACH2. Recombinant protein control fragment (Product #RP-92001). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DACH2,uniProtId:Q96NX9-1,ncbiNodeId:9606,antigenRange:215-333,antigenLength:599,antigenImageFileName:PA5-51369_DACH2_Q96NX9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51369_DACH2_Q96NX9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640366

Product Specific Information

Immunogen sequence: ITAAAMAEAM KLQKMKLMAM NTLQGNGSQN GTESEPDDLN SNTGGSESSW DKDKMQSPFA APGPQHGIAH AALAGQPGIG GAPTLNPLQQ NHLLTNRLDL PFMMMPHPLL PVSLPPASV

Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 59%.

Target Information

This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.