Thermo Fisher Scientific LILRA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CD85g (ILT7). Recombinant protein control fragment (Product #RP-99158). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LILRA4,uniProtId:P59901-1,ncbiNodeId:9606,antigenRange:159-211,antigenLength:499,antigenImageFileName:PA5-61961_LILRA4_P59901-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61961_LILRA4_P59901-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639548

Product Specific Information

Immunogen sequence: DHRLSWTLNS HQHNHGKFQA LFPMGPLTFS NRGTFRCYGY ENNTPYVWSE PSD

Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 52%.

Target Information

ILT7 is a pDC-specific IgG-like transcript and is a member of the leukocyte immunoglobulin-like receptor gene family. This receptor, in complex with FcER1a, transduces ITAM-mediated signals which negatively modulate type I IFN production by pDC. ILT7 is thus a potential target to regulate Type 1 IFN production by pDC, which play a major role during viral infection, auto-immune diseases and anti-cancer immunity. Additionally, ILT7, along with CD123 and BDCA-2, can be used to identify or classify subsets of pDCalong with TLR expression and TLR mediated immune responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.