Thermo Fisher Scientific CD357 (AITR/GITR) Monoclonal Antibody (YGITR765.4.16), Biotin
Mouse GITR(AITR) 단백질을 인식하는 Biotin 결합 Rat Monoclonal 항체로, Flow Cytometry 및 IHC에 사용 가능. 높은 특이성과 재현성을 제공하며, Protein G로 정제된 고순도 항체. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Assay-dependent
Flow Cytometry (Flow)
- 1.0 µg/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | YGITR765.4.16 |
| Immunogen | Mouse GITR transfectant |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539316 |
Additional Formats
Product Specific Information
MA5-17932 targets GITR in FACS and IHC applications and shows reactivity with Mouse samples.
The MA5-17932 immunogen is mouse GITR transfectant.
Target Information
Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also known as GITR or AITR, is encoded by the TNFRSF18 gene located on 1p36.33.
This receptor belongs to the TNF-receptor superfamily and is upregulated upon T-cell activation. It plays a key role in maintaining immunological self-tolerance mediated by CD25(+)/CD4(+) regulatory T cells.
Knockout studies in mice suggest its involvement in CD3-driven T-cell activation and programmed cell death.
Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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