Thermo Fisher Scientific AMACR/p504S Recombinant Rabbit Monoclonal Antibody (AMACR, 4572R)
AMACR/p504S 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 인간 시료 반응성, HEK293 발현 시스템 사용. 고순도 Protein A/G 정제, 안정적 액상 형태로 연구용에 적합.
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Applications
- Western Blot (WB): 1–2 µg/mL
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
- Immunocytochemistry (ICC/IF): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | AMACR, 4572R |
| Immunogen | Recombinant full-length human AMACR protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
P504S/AMACR (α-Methylacyl-CoA Racemase) is an essential enzyme involved in the β-oxidation of branched-chain fatty acids.
High expression of P504S is observed in prostatic adenocarcinoma but not in benign prostate tissue by immunohistochemical staining in paraffin-embedded sections.
Expression is also detected in two premalignant prostate lesions: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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