Thermo Fisher Scientific NAGLU Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NAGLU. Recombinant protein control fragment (Product #RP-93204). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NAGLU,uniProtId:P54802-1,ncbiNodeId:9606,antigenRange:349-459,antigenLength:743,antigenImageFileName:PA5-58551_NAGLU_P54802-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58551_NAGLU_P54802-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644441

Product Specific Information

Immunogen sequence: LQGWLFQHQP QFWGPAQIRA VLGAVPRGRL LVLDLFAESQ PVYTRTASFQ GQPFIWCMLH NFGGNHGLFG ALEAVNGGPE AARLFPNSTM VGTGMAPEGI SQNEVVYSLM A

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

Target Information

This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.