Thermo Fisher Scientific SIRT2 Monoclonal Antibody (PCRP-SIRT2-1A8)
SIRT2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot, ICC/IF, Flow cytometry 등에 사용 가능. Human 시료 반응성. Protein A/G 정제, PBS buffer에 0.05% BSA 및 sodium azide 포함. 연구용으로만 사용.
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- 22933-MSM2-P0
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-SIRT2-1A8 |
| Immunogen | Recombinant full-length human SIRT2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacetylase (NDAC) involved in gene silencing, cell cycle regulation, and DNA damage repair. It may function as a tumor suppressor in human gliomas and serve as a molecular marker for these cells. SIRT2 also acts as a redox sensor regulating muscle gene expression in response to nutrient and exercise stimuli and participates in the phosphorylation cascade during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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