Thermo Fisher Scientific AGK Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AGK. Recombinant protein control fragment (Product #RP-92597). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AGK,uniProtId:Q53H12-1,ncbiNodeId:9606,antigenRange:182-289,antigenLength:422,antigenImageFileName:PA5-62795_AGK_Q53H12-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62795_AGK_Q53H12-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637760

Product Specific Information

Immunogen sequence: IVKGETVPLD VLQIKGEKEQ PVFAMTGLRW GSFRDAGVKV SKYWYLGPLK IKAAHFFSTL KEWPQTHQAS ISYTGPTERP PNEPEETPVQ RPSLYRRILR RLASYWAQ

Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 90%.

Target Information

Lipid kinase that can phosphorylate both monoacylglycerol and diacylglycerol to form lysophosphatidic acid (LPA) and phosphatidic acid (PA), respectively. Does not phosphorylate sphingosine. Overexpression increases the formation and secretion of LPA, resulting in transactivation of EGFR and activation of the downstream MAPK signaling pathway, leading to increased cell growth.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.