Thermo Fisher Scientific SCP2 Polyclonal Antibody
Human SCP2 단백질을 인식하는 Rabbit Polyclonal Antibody로 WB, IHC(P), ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS 기반 용액 형태로 장기 보관 시 -20°C에서 안정적 유지.
- 판매단위
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCP2. Recombinant protein control fragment (Product #RP-94063). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647026 |
Product Specific Information
Immunogen sequence:
IKMVGFDMSK EAARKCYEKS GLTPNDIDVI ELHDCFSTNE LLTYEALGLC PEGQGATLVD RGDNTYGGKW VINPSGGLIS KG
Highest antigen sequence identity to the following orthologs:
- Mouse: 91%
- Rat: 93%
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
- The proximal promoter encodes the longer SCPx protein.
- The distal promoter encodes the shorter SCP2 protein, sharing a common C-terminus.
SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids, while SCP2 functions as an intracellular lipid transfer protein.
This gene is highly expressed in organs related to lipid metabolism and may be implicated in Zellweger syndrome, characterized by peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing generates multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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