Thermo Fisher Scientific Human IDH2 Synthetic Peptide
Human IDH2 단백질의 N말단 17개 아미노산에 대응하는 합성 펩타이드로, PA5-20977 항체의 블로킹 펩타이드로 사용 가능. Human 종에 반응하며 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the amino terminus of human IDH2.
PEP-1091 can be used as a blocking peptide with polyclonal antibody PA5-20977.
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD and the other NADP as electron acceptors.
Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases localized to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases—one mitochondrial and one predominantly cytosolic.
Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in the mitochondria, playing a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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