![Thermo Fisher Scientific Human ABL1 [F317L], GST Tag Recombinant Protein](https://images.cacheby.com/product-images-normalized/shared/857c0ec6cfd00134.png?s=800x800&t=contain&q=82&f=webp)
Thermo Fisher Scientific Human ABL1 [F317L], GST Tag Recombinant Protein
ABL1 F317L 변이형 인간 재조합 단백질로, GST 태그가 부착되어 있으며 Z'-LYTE™ kinase assay에 검증됨. 곤충 세포에서 발현된 활성형 단백질로 연구용으로 사용. -80°C 보관, SelectScreen™ Kinase Profiling Service에서도 이용 가능.
- 카탈로그번호
- 3개 옵션
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human ABL1 [F317L], GST Tag Recombinant Protein
Thermo Fisher Scientific Human ABL1 [F317L], GST Tag Recombinant Protein
Applications
- Kinase Assay (KA)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Insect cells |
| Amino Acid Sequence | 27-end |
| Tag | GST-tag |
| Molecular Weight | 146.3 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris HCl (pH 7.5), 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 0.1 mM EDTA, 10 mM glutathione, 25% glycerol |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
- For maximum recovery, spin prior to use.
- Aliquots below 20 µL are not recommended.
- Do not store kinase diluted.
- Properly stored at -80°C, guaranteed for 6 months from date of purchase.
- Expressed in insect cells (ABL1 F317L recombinant human protein, 27-end).
- Available in multiple pack sizes for convenient use.
- Also available through SelectScreen™ Kinase Profiling Service.
- Validated for use with the Z'-LYTE™ assay.
Protein Form: Recombinant, Active, Mutant
Gene Accession Number: NP_005148.2
Target Information
ABL1 cytoplasmic tyrosine kinase protooncogene encodes a cytoplasmic and nuclear kinase involved in cell differentiation, division, adhesion, and stress response. Activity is negatively regulated by its SH3 domain; deletion of SH3 converts ABL1 into an oncogene. The BCR-ABL1 fusion is found in many cases of chronic myelogenous leukemia. CDK1-mediated phosphorylation regulates the DNA-binding activity of ABL1, suggesting a role in the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.