Thermo Fisher Scientific Phospho-HDAC4/HDAC5/HDAC7 (Ser246, Ser259, Ser155) Monoclonal Antibody (B.544.8)
HDAC4/HDAC5/HDAC7 단백질의 인산화 형태(Ser246, Ser259, Ser155)를 특이적으로 인식하는 단일클론 항체입니다. Western blot 및 ChIP assay에 적합하며, 인간과 생쥐 시료에 반응합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
ChIP assay (ChIP)
- Tested Dilution: 1–3 µL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B.544.8 |
| Immunogen | Synthetic phosphopeptide corresponding to pSer155 of human HDAC7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10980952 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
The protein encoded by this gene has sequence homology to members of the histone deacetylase family.
This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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