Thermo Fisher Scientific Phospho-HDAC4/HDAC5/HDAC7 (Ser246, Ser259, Ser155) Monoclonal Antibody (B.544.8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

ChIP assay (ChIP)

1-3 µL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

B.544.8

Immunogen

Synthetic phosphopeptide corresponding to pSer155 of human HDAC7 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC4/HDAC5/HDAC7,uniProtId:Q8WUI4-1,ncbiNodeId:9606,antigenRange:155,antigenLength:952,antigenImageFileName:MA5-14776_HDAC4HDAC5HDAC7_Q8WUI4-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14776_HDAC4HDAC5HDAC7_Q8WUI4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_10980952

Product Specific Information

It is not recommended to aliquot this antibody.

Target Information

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.