Thermo Fisher Scientific Doublecortin Polyclonal Antibody
Doublecortin 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. 인간 시료 반응성, 염색 및 세포 분석용으로 사용 가능. 높은 특이성과 안정성 제공. 연구용으로만 사용.
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Thermo Fisher Scientific Doublecortin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 6 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence DRSHCQSLRFHQN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933350 |
Product Specific Information
This antibody is expected to recognize reported isoform a (NP_000546.2) only.
Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
In the developing cortex, cortical neurons migrate over long distances to reach their final differentiation sites.
DCX (Doublecortin) is a cytoplasmic protein that directs neuronal migration by regulating microtubule organization and stability.
It contains two doublecortin domains that bind microtubules and interacts with LIS1, a regulatory gamma subunit of platelet activating factor acetylhydrolase.
This interaction is essential for proper microtubule function in the developing cortex.
Mutations in the DCX gene cause X-linked lissencephaly.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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