Thermo Fisher Scientific NOTCH1 Polyclonal Antibody
Human NOTCH1 단백질을 인식하는 염소 유래 폴리클로날 항체로, IHC(P) 및 ICC/IF에 사용 가능. 0.5 mg/mL 농도의 액상 형태이며, TBS(pH 7.3) 버퍼에 0.5% BSA와 0.02% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence HGPTCRQDVNEC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933351 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
The NOTCH1 gene belongs to a family of epidermal growth factor (EGF)-like homeotic genes that encode transmembrane proteins with a variable number of cysteine-rich EGF-like repeats in the extracellular region. Four Notch genes have been described in mammals: Notch1, Notch2, Notch3, and Notch4 (Int-3), which are implicated in the differentiation of the nervous system and other structures.
The EGF-like proteins Delta and Serrate have been identified as ligands of Notch1. Mature Notch proteins are heterodimeric receptors derived from the cleavage of Notch pre-proteins into an extracellular subunit (NEC) containing multiple EGF-like repeats and a transmembrane subunit including the intracellular region (Ntm).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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