Thermo Fisher Scientific ADNP Polyclonal Antibody
ADNP 단백질을 특이적으로 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 Immunocytochemistry에 적합. 인간 및 마우스 시료 반응성. Affinity chromatography로 정제된 액상 제품이며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunocytochemistry (ICC/IF): 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADNP (Accession Q9H2P0), corresponding to amino acid residues I125–P175 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818154 |
Product Specific Information
Antibody detects endogenous levels of total ADNP.
Target Information
Vasoactive intestinal peptide (VIP) is a neuroprotective factor that can stimulate or inhibit tumor cell growth depending on the cell type. The ADNP gene encodes a protein upregulated by VIP, potentially mediating its stimulatory effects on certain tumor cells. The protein includes one homeobox and nine zinc finger domains, suggesting a role as a transcription factor. It is also upregulated in normal proliferative tissues and may enhance cell viability by modulating p53 activity. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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