Thermo Fisher Scientific HDAC1 Monoclonal Antibody (OTI6F11), TrueMAB
HDAC1 단백질을 표적으로 하는 Thermo Fisher Scientific의 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 인간 유래 단백질을 면역원으로 제작되었으며, 고순도의 친화 크로마토그래피 정제 및 동결건조 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F11 |
| Immunogen | Full-length human recombinant protein of HDAC1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in regulating eukaryotic gene expression.
HDAC1, a member of the histone deacetylase family, is a component of the histone deacetylase complex and interacts with the retinoblastoma tumor-suppressor protein.
This interaction is crucial for controlling cell proliferation and differentiation.
Together with metastasis-associated protein-2, HDAC1 deacetylates p53 and modulates its effects on cell growth and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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