Thermo Fisher Scientific HYD Polyclonal Antibody
Rabbit polyclonal antibody targeting human EDD protein. Validated for Western blot and IHC (paraffin) applications. Unconjugated form with 1 mg/mL concentration. Suitable for research use in studying ubiquitin-protein ligase function.
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- PA538247
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- pk
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Thermo Fisher Scientific HYD Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the internal region of human EDD |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2554849 |
Target Information
EDD (E3 identified by Differential Display) is a progestin-regulated gene isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be the human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor required for imaginal disc growth control.
EDD contains a HECT domain at the carboxy terminus. HECT domain-containing proteins act as ubiquitin-protein ligases (E3 enzymes). EDD has been shown to bind ubiquitin and may function as an E3 ubiquitin-protein ligase, similar to other HECT family proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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