Thermo Fisher Scientific SEC62 Polyclonal Antibody
SEC62 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol)로 제공됩니다. 인간 단백질에 반응하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SEC62. Recombinant protein control fragment (Product #RP-90914) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647084 |
Product Specific Information
Immunogen sequence:
GGRHHFWFLP NLTADVGFID SFRPLYTHEY KGPKADLKKD EKSETKKQQK SDSEEKSDSE KKEDEEGKVG PGNHGTEGSG GERHSDTDSD RREDDRSQHS SGNGNDFEMI TKEELEQQTD GDCEEDEEEE NDGETPKSS
Sequence identity:
- Mouse: 91%
- Rat: 90%
Target Information
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are associated with ribosome-free SEC61 complex. It is speculated that Sec61–Sec62–Sec63 may perform post-translational protein translocation into the ER and may also mediate the retrograde transport of ER proteins for degradation via the ubiquitin-proteasome pathway. The encoded protein is an integral membrane protein located in the rough ER.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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