Thermo Fisher Scientific PROZ Monoclonal Antibody (OTI1C10), TrueMAB
Human PROZ 단백질을 표적으로 하는 Mouse IgG2a 단일클론 항체로 Western blot에 최적화됨. Unconjugated 형태로 제공되며, 고순도 친화 크로마토그래피로 정제. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 안정적 유지.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 115–400 of human PROZ produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PROZ (Protein Z) is a vitamin K-dependent plasma glycoprotein (~62 kDa, 396 amino acids). It consists of four domains: a Gla-rich region, two EGF-like domains, and a trypsin-like domain. Although structurally related to serine proteases (factors VII, IX, X, and protein C), it lacks catalytic activity due to absence of the serine residue.
Protein Z participates in the coagulation cascade by facilitating degradation of factor Xa via the protein Z-dependent protease inhibitor (ZPI). Deficiency states have been variably associated with thrombosis or bleeding tendencies. Its activity is impaired under warfarin therapy due to vitamin K dependency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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