Thermo Fisher Scientific PPP2R5D Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.04–0.4 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Immunogen sequence:
PKVAKCTAKP SSSGKDGGGE NTEEAQPQPQ PQPQPQAQSQ PPSSNKRPSN STPPPTQLSK IKYSGGPQIV KKERRQSSSR FNLSKNRELQ KLPAL

Target Information

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression.
ZNF265 (Zinc finger protein 265), also known as ZRANB2 (Zinc finger Ran-binding domain-containing protein 2), ZIS, ZIS1 or ZIS2, is a 330 amino acid protein that belongs to the ZRANB2 family.
Localized to the nucleus, ZNF265 functions as a splicing factor responsible for alternatively splicing Tra-2 beta transcripts and may interfere with constitutive 5'-splice selection.
ZNF265 contains two RanBP2-type zinc fingers through which it conveys its RNA-binding activity. Two isoforms, designated ZIS-1 and ZIS-2, are expressed due to alternative splicing events. Upon DNA damage, ZIS-2 may be phosphorylated by ATM or ATR.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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