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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI3H7), TrueMAB
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Thermo Fisher Scientific

Thermo Fisher Scientific XPF Monoclonal Antibody (OTI3H7), TrueMAB

상품 한눈에 보기

ERCC4(XPF) 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 Flow cytometry에 적합합니다. HEK293T에서 생산된 full-length human recombinant protein을 면역원으로 사용했으며, 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능합니다.

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Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 08. 05. 오전 08:49
Thermo Fisher Scientific TA503163 XPF Monoclonal Antibody (OTI3H7), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI3H7), TrueMAB

Applications

Western Blot (WB)

  • Tested Dilution: 1:1,000
  • Publications: - References

Flow Cytometry (Flow)

  • Tested Dilution: 1:100
  • Publications: - References

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI3H7
Immunogen Full length human recombinant protein of human ERCC4 produced in HEK293T cell
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA:

  • Nucleotide excision repair (NER) for UV-induced lesions and bulky chemical adducts
  • Recombination repair of genotoxic interstrand cross-links

NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3′ of the DNA lesion while the ERCC1/XPF complex makes the 5′ incision. ERCC1/XPF also likely participates in processing partially processed recombination intermediates.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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