Thermo Fisher Scientific CysLTR1 (extracellular) Polyclonal Antibody, FITC

Applications

• Flow Cytometry (Flow)
  Tested Dilution: 2.5 µg

Product Specifications

Product Specific Information

• Reconstitution: 50 µL double distilled water (DDW), depending on sample size
• Ships as lyophilized powder at room temperature
• Upon arrival, store at -20°C
• Reconstituted solution stable at 4°C for up to 1 week
• For long-term storage, aliquot and store at -20°C
• Avoid multiple freezing and thawing cycles
• Centrifuge all antibody preparations before use (10,000 × g, 5 min)

Target Information

The cysteinyl leukotrienes (LTC4, LTD4, and LTE4) are important mediators of human bronchial asthma. Pharmacologic studies have shown that cysteinyl leukotrienes activate at least two receptors: CysLTR1 and CysLTR2.
CysLTR1 is a G protein-coupled receptor, and its activation by LTD4 results in smooth muscle contraction and proliferation, edema, eosinophil migration, and damage to the mucus layer in the lung.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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