Thermo Fisher Scientific RNF12 Polyclonal Antibody
Human RNF12 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제. PBS, 40% glycerol, 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RLIM. Recombinant protein control fragment (Product #RP-92141). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789800 |
Product Specific Information
Immunogen sequence:
RSESTSARPS RSERNSTEAL TEVPPTRGQR RARSRSPDHR RTRARAERSR SPLHPMSEIP RRSHHSISSQ TFEHPLVNET EGSSRTRHHV TLRQQISGPE LLSRGLFAAS GTRNASQGAG SSDTAASGES TGSGQRPPTI VLDL
Target Information
RNF12 is a RING-H2 zinc finger protein functioning as a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), leading to proteasome-dependent degradation of LDB1.
RNF12 and LDB1 act as co-repressors of LHX1/LIM-1, a homeodomain transcription factor.
Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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