Thermo Fisher Scientific ssPA Polyclonal Antibody

Thermo Fisher Scientific ssPA Polyclonal Antibody

Applications

• ELISA (ELISA)
  Tested Dilution: 1:1,000–1:2,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for E. coli ssPA/Stringent starvation protein A.

Target Information

sspA preferentially cleaves peptide bonds on the carboxyl-terminal side of aspartate and glutamate. Along with other extracellular proteases, it is involved in colonization and infection of human tissues.
Required for proteolytic maturation of thiol protease SspB and inactivation of SspC, an inhibitor of SspB.
It is the most important protease for degradation of fibronectin-binding protein (FnBP) and surface protein A, which are involved in adherence to host cells.
May also protect bacteria against host defense mechanisms by cleaving the immunoglobulin classes IgG, IgA, and IgM.
May be involved in the stability of secreted lipases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.