Thermo Fisher Scientific GRPEL2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GRPEL2. Recombinant protein control fragment (Product #RP-91014). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRPEL2,uniProtId:Q8TAA5-1,ncbiNodeId:9606,antigenRange:132-221,antigenLength:225,antigenImageFileName:PA5-53747_GRPEL2_Q8TAA5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-53747_GRPEL2_Q8TAA5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642223

Product Specific Information

Immunogen sequence: EPEDQKLTLE KVFRGLLLLE AKLKSVFAKH GLEKLTPIGD KYDPHEHELI CHVPAGVGVQ PGTVALVRQD GYKLHGRTIR LARVEVAVES

Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.

Target Information

GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.