Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI5B11), TrueMAB
TYMP 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin)에 적합합니다. Human 시료에 반응하며, 고순도의 Affinity chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
A platelet-derived endothelial growth factor (PD-ECGF), also known as thymidine phosphorylase (TP) or gliostatin. In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It acts as a chemotactic and mitogenic factor for endothelial cells and is a non-heparin-binding angiogenic factor present in platelets. TYMP is also involved in the transformation of fluoropyrimidines, cytotoxic agents used in cancer treatment, into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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