Thermo Fisher Scientific HBS1L Monoclonal Antibody (OTI2A3), TrueMAB
HBS1L 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. Human 시료 반응성. Affinity chromatography로 정제된 액상 항체. PBS, BSA, glycerol buffer에 보존되며 -20°C에서 보관.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–242 of human HBS1L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the GTP-binding elongation factor family. It is expressed in multiple tissues, with the highest expression in heart and skeletal muscle.
The intergenic region of this gene and the MYB gene has been identified as a quantitative trait locus (QTL) controlling fetal hemoglobin level. This region influences erythrocyte, platelet, and monocyte counts as well as erythrocyte volume and hemoglobin content.
DNA polymorphisms in this region are associated with fetal hemoglobin levels and pain crises in sickle cell disease. A single nucleotide polymorphism in exon 1 of this gene is significantly associated with severity in beta-thalassemia/Hemoglobin E. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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