Thermo Fisher Scientific PUS10 Polyclonal Antibody
Thermo Fisher Scientific의 PUS10 폴리클로날 항체로 인간 PUS10 단백질을 인식합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PUS10. Recombinant protein control fragment (Product #RP-99688) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646150 |
Product Specific Information
Immunogen sequence:
NSPKAVCAVL EIECAHGAVF VAGRYNKYSR NLPQTPWIID GERKLESSVE ELISDHLLAV FKAESFNFSS SGREDVDVRT LGNGRPFAIE LVNPHRVHFT SQEIKE
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 92%
Target Information
Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs.
PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable).
Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage.
Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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