Thermo Fisher Scientific BAG5 Polyclonal Antibody
BAG5 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC(P), IP에 적합. 다양한 종(Bovine, Dog, Human, Mouse, Rat)에 반응. Unconjugated 형태의 액상 제품이며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to amino acids 168–187 of human BAG-5 (GenBank no. gi 6631077, ref NP_004864.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2718752 |
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function. BAG-5 is believed to play an important role in neuronal death mechanisms and may act as a modulator of the hsp70/hsp40 chaperone axis. It may also coordinate localization or modulation of other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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