Thermo Fisher Scientific ZNF322A Polyclonal Antibody

Thermo Fisher Scientific ZNF322A Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:3,000
Publications: –

Product Specifications

Product Specific Information

• Recommended positive controls: Mouse heart, Rat muscle
• Predicted reactivity: Rhesus Monkey (98%), Chimpanzee (99%), Bovine (93%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

ZNF322 contains four exons and spans 23.2 kb in chromosome 6p22.1 region, and transcribes a 2.7 kb mRNA encoding a protein with 402 amino acid residues.
Through northern blot analysis, ZNF322 was shown to be expressed in every human tissue examined at adult stage and during embryonic developmental stages (80 days to 24 weeks).
When ZNF322 was overexpressed in COS-7 cells, ZNF322-EGFP fusion protein was detected in the nucleus and cytoplasm. Reporter gene assays showed that ZNF322 is a transcriptional activator.
Furthermore, overexpression of ZNF322 in COS-7 cells activates the transcriptional activity of SRE and AP-1.
Together, these results suggest that ZNF322 is a member of the zinc-finger transcription factor family and may act as a positive regulator in gene transcription mediated by MAPK signaling pathways.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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