Thermo Fisher Scientific hnRNP L Polyclonal Antibody
Human hnRNP L 단백질을 인식하는 Rabbit Polyclonal 항체. Western blot, IHC(P), ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HNRNPL (Product #RP-103130). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791271 |
Product Specific Information
Immunogen sequence:
DTWDYTNPNL SGQGDPGSNP NKRQRQPPLL GDHPAEYGGP HGGYHSHYHD EGYGPPPPHY EGRRMGPPVG GHRRGPSRY
Target Information
Heterogeneous nuclear RNAs (hnRNAs), including mRNA precursors and mature mRNAs, associate with specific proteins to form heterogeneous ribonucleoprotein (hnRNP) complexes.
Heterogeneous nuclear ribonucleoprotein L (hnRNP L) is one of the proteins stably associated with hnRNP complexes and plays a major role in the formation, packaging, processing, and function of mRNA.
It is present in the nucleoplasm as part of the HNRP complex, but HNRP proteins have also been identified outside of the nucleoplasm.
Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins shuttle between the nucleus and cytoplasm, they may also have cytoplasmic functions.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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