
Thermo Fisher Scientific p300 Monoclonal Antibody (NM-11)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
View 3 publications 3 publications
Immunohistochemistry (IHC)
Assay-dependent
Immunocytochemistry (ICC/IF)
1:100
Flow Cytometry (Flow)
-
View 1 publication 1 publication
Immunoprecipitation (IP)
Assay-dependent
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human, Mouse
Published species
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
NM-11
Immunogen
Recombinant human p300 protein
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2533138
Target Information
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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