Thermo Fisher Scientific c-Myc Monoclonal Antibody (9E10), Alexa Fluor 555
Alexa Fluor 555로 결합된 c-Myc 단일클론 항체(클론 9E10). Western blot, ICC/IF, Flow cytometry에 적합. 인간 c-Myc 단백질에 특이적이며, 형광 검출에 최적화된 고품질 항체. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:25–1:100 | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9E10 |
| Immunogen | Synthetic peptide A(408)EEQKLISEEDLLRKRREQLKHLEQLRNSCA(438) of human c-Myc |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609820 |
Additional Formats
Target Information
The c-Myc protein is a 62 kDa transcription factor encoded by the c-Myc gene on human chromosome 8q24. It is commonly activated in various tumor cells and plays a key role in cellular proliferation, differentiation, apoptosis, and cell cycle progression.
Phosphorylation at Thr58/Ser62 by kinases such as GSK3, CDK, ERK2, and JNK is associated with regulation of cell proliferation and cycle progression.
c-Myc is essential for vasculogenesis and angiogenesis during tumor development.
Overexpression or translocation of the c-Myc gene is implicated in multiple human cancers, including lung, breast, and colon carcinomas, as well as Burkitt’s lymphoma.
Antibodies against c-Myc epitopes recognize Myc-tagged fusion proteins, enabling detection of recombinant proteins in various assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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