Thermo Fisher Scientific TNRC4 Polyclonal Antibody
TNRC4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC(P) 및 ICC/IF에 사용 가능. 고순도의 항원 친화 크로마토그래피 정제, 안정적인 PBS/glycerol 버퍼 제공. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TNRC4. Recombinant protein control fragment (Product #RP-89180). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648798 |
Product Specific Information
Immunogen sequence:
PVSAIPAALG VNGYSPVPTQ PTGQPAPDAL YPNGVHPYPA QSPAAPVDPL QQAYAGMQHY TAAYPAAYSL VAPAFPQPPA LVAQQPPPPP QQQQQQQQQQ QQQQQREGPD GCNIFIYHLP QEFTDSEILQ MFV
- Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 94%
Target Information
RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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