Thermo Fisher Scientific BMPR1A Polyclonal Antibody
BMPR1A 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체. 인간 및 생쥐 반응성, Western blot에 최적화. Goat IgG 기반, 비결합형 액상 제품으로 안정적인 신호 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
- Publications: [References not available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KSDSDQKKSEN) corresponding to the internal amino acids of BMPR1A (aa 36–46) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10980930 |
Product Specific Information
- Predicted to react with canine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
BMPR1A is a Type I member of the TGF-beta receptor superfamily of transmembrane serine/threonine kinases that phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are closely related to activin receptors (ACVR1 and ACVR2).
Ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through heteromeric complexes of type I (50–55 kD) and type II (70–80 kD) receptors. Type II receptors bind ligands independently, but require type I receptors for signaling, whereas type I receptors need type II receptors for ligand binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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