Thermo Fisher Scientific HIST1H2BA Monoclonal Antibody (OTI1C9)
HIST1H2BA 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 인간 반응성, Mouse IgG1 아이소타입이며 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제, 안정적 PBS 버퍼 보존.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–127 of HIST1H2BA produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723239 |
Target Information
Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells. It replaces classical histone H2B prior to nucleosome-to-protamine transition and likely acts as a nucleosome dissociating factor, creating dynamic chromatin for histone exchange.
Also expressed maternally and found in the female pronucleus, suggesting a similar role in protamine replacement during fertilization.
Detected in fat cells, though its specific functions and modifications remain unclear.
Core component of nucleosome; histones regulate transcription, DNA repair, replication, and chromosomal stability through post-translational modifications and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 항원 구조 관련 이미지: MA5-26966_HIST1H2BA_Q96A08-1_House_mouse.svg / MA5-26966_HIST1H2BA_Q96A08-1_House_mouse_PDP.jpeg)
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