Thermo Fisher Scientific VPS37A Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–10 µg/mg lysate

Product Specifications

Product Specific Information

• The recommended shelf life for this product is 1 year from date of receipt.

Target Information

This gene belongs to the VPS37 family, encoding a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex. It is required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies.
Expression of this gene is downregulated in hepatocellular carcinoma, and mutations are associated with autosomal recessive spastic paraplegia-53.
A related pseudogene has been identified on chromosome 5, and alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.