Thermo Fisher Scientific MARCKSL1 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로, MARCKSL1 단백질을 검출. Western Blot 및 Immunohistochemistry에 적합. 고순도 Affinity chromatography 정제, 액상 형태로 안정적인 저장 가능. 연구용으로만 사용.
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Thermo Fisher Scientific MARCKSL1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MARCKSL1 (Accession P49006), corresponding to amino acid residues E84–C134 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852650 |
Product Specific Information
Antibody detects endogenous levels of total MRP.
Target Information
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein localized to the plasma membrane and serves as a major cellular substrate for protein kinase C (PKC).
MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein that, like MARCKS, is a major substrate for PKC.
It is expressed in various tissues, with highest levels in testis and uterus, and participates in membrane–cytoskeletal signaling events such as secretion, migration, phagocytosis, and cell adhesion.
Additionally, MARCKSL1 functions as a regulator of Integrin activation and is thought to regulate Integrin-dependent signal transduction pathways, particularly those involved in macrophage spreading.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-103304_MARCKSL1_P49006-1_Rabbit.svg, PA5-103304_MARCKSL1_P49006-1_Rabbit_PDP.jpeg)
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