Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI3A4), TrueMAB
인간 PDE2A 단백질을 인식하는 단일클론 항체로, WB, IHC, ICC/IF, Flow Cytometry에 적합합니다. TrueMAB 형식의 Mouse IgG2b 항체이며, 동결건조 형태로 제공되어 안정적 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Full length human recombinant PDE2A protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase with three isoforms (PDE2A1, PDE2A2, PDE2A3) generated by alternative splicing. It degrades both cAMP and cGMP, showing higher activity toward cGMP. PDE2A is expressed in multiple tissues, predominantly in the brain, including the cerebellum and neocortex. It has been implicated in erectile dysfunction and regulation of endothelial fluid and inflammatory cell transport.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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