Thermo Fisher Scientific FKBP135 Polyclonal Antibody
FKBP135 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성이 있으며, Protein A로 정제된 1 mg/mL 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific FKBP135 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human FKBP135, amino acids 25–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FKBP15, also known as FKBP133, is a member of the FK506-binding protein family, initially identified as immunophilins—targets for immunosuppressant drugs FK506 and Rapamycin. FKBP15 is expressed in the developing nervous system and contains a WH1 domain similar to Wiskott-Aldrich syndrome protein. It co-localizes with F-actin in growth cones of dorsal root ganglion neurons and modulates growth cone behavior. FKBP15 associates with both microtubules and actin filament systems, and its disruption delays early endosome transport in HeLa cells, indicating involvement in endosomal transport. At least three isoforms of FKBP15 are known.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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