Thermo Fisher Scientific SERPINA3 Polyclonal Antibody
Human SERPINA3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 IHC(P) 검증 완료. 고순도 항원 친화 크로마토그래피 정제. 장기보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific SERPINA3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SERPINA3. Recombinant protein control fragment (Product #RP-98838). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789063 |
Product Specific Information
Immunogen sequence:
LASANVDFAF SLYKQLVLKA PDKNVIFSPL SISTALAFLS LGAHNTTLTE ILKGLKFNLT ETSEAEIHQS FQHLLRTLNQ SSDELQLSMG NAMFVKEQLS LLDRFTEDAK RLYGSEAFAT DFQDSAAAKK LINDYVKNGG APHR
Target Information
SERPINA encodes Alpha 1-ACT, an early-stage acute-phase plasma protein and serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase.
Alpha-1-ACT, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer’s disease (AD) and in normal aged human and monkey brain.
Regulation of serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation.
Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to Alpha-1-ACT.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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