Thermo Fisher Scientific FBXO32 Polyclonal Antibody
FBXO32 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 사용 가능하며 인간 및 마우스 반응성 확인. 합성 펩타이드 면역원 기반, 액상 형태로 제공. 근위축 관련 연구용으로 적합.
- 카탈로그번호
- PA543915
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human FBXO32 (aa 207–256) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606204 |
Product Specific Information
Peptide sequence:
QQQLNNIQIT RPAFKGLTFT DLPLCLQLNI MQRLSDGRDL VSLGQAAPDL
Sequence homology:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 100%
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid F-box motif. F-box proteins form part of the SCF ubiquitin ligase complex, which functions in phosphorylation-dependent ubiquitination.
F-box proteins are divided into three classes:
- Fbws – containing WD-40 domains
- Fbls – containing leucine-rich repeats
- Fbxs – containing other interaction modules or no recognizable motifs
The encoded protein belongs to the Fbxs class and contains an F-box domain. It is highly expressed during muscle atrophy, and mice deficient in this gene resist atrophy, making it a potential drug target for muscle atrophy treatment. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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