Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Perilipin 1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 Affinity chromatography로 정제되었으며, 인체·마우스·랫트 반응성. 액상 형태로 -20°C 보관.
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Thermo Fisher Scientific Perilipin 1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human PLIN1 (Accession O60240), amino acids F500–K520 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903378 |
Product Specific Information
Antibody detects endogenous levels of total Perilipin-1.
Target Information
Adipose tissue serves as a regulated energy reserve. Adipose cells secrete physiologically important proteins such as lipoprotein lipase (LPL), leptin, Acrp30, resistin, and perilipin.
Perilipin is an intracellular neutral lipid droplet protein localized to the surface of lipid droplets and regulated hormonally. Upon lipolytic stimulation, perilipin is phosphorylated by protein kinase A, inhibiting hormone-sensitive lipase (HSL), which mediates triacylglycerol hydrolysis.
Perilipin expression is limited to adipocytes and steroidogenic cells, with two known isoforms (A and B) produced by differential splicing of a single-copy gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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