Thermo Fisher Scientific CCP110 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 CCP110 단백질을 인식합니다. Western blot에 최적화되어 있으며, 세포 중심체 복제 및 섬모 형성 조절 연구에 적합합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA568140
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CCP110 Polyclonal Antibody
Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human CCP110 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2691982 |
Product Specific Information
Predicted to react with Human samples.
Target Information
Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole, thereby preventing cilia formation (PubMed:17719545, PubMed:17681131, PubMed:23486064).
Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA), thereby affecting the fusion of recycling endosomes to basal bodies during cilia formation.
Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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