Thermo Fisher Scientific PDIA6 Monoclonal Antibody (3B4)

Applications

• Western Blot (WB): 1:500–1:1,000
• ELISA (ELISA): 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of PDIA6 protein:

MALLVLGLVS CTFFLAVNGL YSSSDDVIEL TPSNFNREVI QSDSLWLVEF YAPWCGHCQR LTPEWKKAAT ALKDVVKVGA VDADKHHSLG GQYGVQGFPT IKIFGSNKNR PEDYQGGRTG EAIVDAALSA LRQLVKDRLG GRSGGYSSGK QGRSDSSSKK DVIELTDDSF DRNVLDSEDV WMVEFYAPWC GHCKNLEPEW AAAASEVKEQ TKGKVKLAAV DATVNQVLAS RYGIRGFPTI KIFQKGESPV DYDGGRTRSD IVSRALDLFS DNAPPPELLE IINEDIAKRT CEEHQLCVVA VLPHILDTGA AGRNSYLEVL LKLADKYKKK MWGWLWTEAG AQSELETALG IGGFGYPAMA AINARKMKFA LLKGSFSEQG INEFLRELSF GRGSTAPVGG GAFPTIVERE PWDGRDGELP VEGDIDLSDV ELDDLGKDEL

Target Information

P5 (PDIA6) is a novel human protein with peptide-binding and chaperone activity specific to certain proteins. It shares structural similarities with PDI, an endoplasmic reticulum (ER) protein. The deduced sequence includes the ER retention signal KDEL and two CXXC-like motifs responsible for oxidoreductase activity—one at each terminus. The N-terminal CXXC motif is more critical for isomerase activity. Unlike other PDI-like proteins, P5 is not stress-inducible.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.