Thermo Fisher Scientific WDR48 Polyclonal Antibody
WDR48 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin)에서 검증됨. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS와 50% glycerol buffer에 보존. 세포 신호전달 및 탈유비퀴틴화 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human WDR48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719930 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
WD-repeats are conserved motifs (40–60 amino acids) found in many proteins forming a propeller-like tertiary structure. Proteins containing WD-repeats play roles in signal transduction, apoptosis, transcriptional regulation, and cell cycle control.
WDR48 (WD repeat-containing protein 48), also known as USP1-associated factor 1 (p80), is a 677 amino acid protein with eight WD repeats. It regulates deubiquitinating complexes by activating USP1, USP12, and USP46, enhancing catalytic turnover without altering substrate affinity.
WDR48 is ubiquitously expressed and mainly localized in the cytoplasm. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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