Thermo Fisher Scientific NR1I3 Monoclonal Antibody (OTI8E3), TrueMAB
Human NR1I3 단백질(1-236 aa)에 특이적인 마우스 단일클론 항체로, Western blot에 적합. TrueMAB 포맷으로 1 mg/mL 농도, PBS/BSA/glycerol buffer에 저장. 약물 대사 및 빌리루빈 제거 관련 핵수용체 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–236 of human NR1I3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism.
The protein binds to DNA as a monomer or as a heterodimer with the retinoid X receptor and regulates transcription of target genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but can be modulated by both agonists and inverse agonists.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: TA805367_MB67_Q14994-1_House_mouse.svg, TA805367_MB67_Q14994-1_House_mouse_PDP.jpeg)
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배송/결제/교환/반품 안내
배송 정보
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